TRT, is committed to neovascularization and increasing collateral pathways within the myocardium. The use of SoftWave® therapy directly on the surface of the heart shows preliminary results of increased blood flow, increase in the ejection fraction and a marked improvement in cardiac performance.
TRT is nearing completion of its initial animal trials using our SoftWave™ technology to treat cardiovascular disease in rat and pig hearts. Dr. Michael Grimm of the University of Vienna is directing these studies and has already submitted his protocol for human treatment to the Ethical Committee for approval.
This device is not yet approved for distribution or use in the United States.
Shock waves against heart failure - The therapy is known from orthopedics or the destruction of kidney stones. It is completely new in cardiac surgery.
Shockwave therapy induces tissue regeneration in infarcted heart muscle and thereby significantly improves heart function (left ventricular ejection fraction).
Shockwaves at low-energy levels are in broad clinical use for tissue regeneration in other indications, mainly in orthopedics (see International Society of Medical Shockwave Treatment – www.ismst.com). It is therefore proven safe in millions of patients over more than 30 years. This distinguishes shockwave therapy clearly from all other regenerative therapy approaches!
While establishing cardiac shockwave therapy for the intraoperative use in cardiac surgery we are in parallel developing a second generation heart applicator for minimally-invasive/ interventional use in cardiology.
Dr. Michael Grimm of the University of Vienna using CardioGold to regenerate heart tissue cells.
miR-19a-3p containing exosomes improve function of ischaemic myocardium upon shock wave therapy - As many current approaches for heart regeneration exert unfavourable side effects, the induction of endogenous repair mechanisms in ischaemic heart disease is of particular interest. Recently, exosomes carrying angiogenic miRNAs have been described to improve heart function. More..